|The Kryptonian Cure|
|Season 4, Episode 1|
|City On Fire||Brain On Fire|
The Kryptonian Cure is the first episode of Supergirl Season 4 and the 65th episode overall. It is the first part of the 9-part WAR OF THE SUPERMEN storyline.
A FATAL DEMONSTRATION- Lex Luthor and Lillian Luthor travel to D.C. to showcase D.I.S.C.O.R.D., the "golden girl" of Project Prometheus, as Dru-Zod formally declares war on Earth and humanity. At the DEO, Kara Danvers, Alex Danvers, Winn Schott, Lena Luthor, and Maggie Sawyer pick up the pieces from the destruction and havoc wreaked by the anti-Kryptonian terrorists.
- Melissa Benoist as Kara Danvers/Supergirl
- Chyler Leigh as Alex Danvers/Batwoman
- Jeremy Jordan as Winn Schott
- Katie McGrath as Lena Luthor
- Laura Benanti as Astra In-Ze
- Tyler Hoechlin as Kal-El
- Jenna Dewan-Tatum as Lucy Lane/Superwoman
- Floriana Lima as Maggie Sawyer
- with Claire Holt as Karen Starr/Power Girl
- and Mechad Brooks as James Olsen/Guardian
Special Appearance By
- Calista Flockhart as Cat Grant
Special Guest Stars
- Peter Facinelli as Maxwell Lord (Earth-38)
- with Helen Slater as Eliza Danvers
- and Zachary Quinto as General Dru-Zod
- Lauren German as President Veronica Banks
- Casper Crump as Vandal Savage (Earth-2)
- Brenda Strong as Lillian Luthor
- Katheryn Winnick as D.I.S.C.O.R.D.
- Glenn Morshower as General Sam Lane
- Minka Kelly as Lois Lane
- Briana Venskus as Agent Susan Vasquez
- with Sarah Shahi as Ursa
- and Michael Rosenbaum as Lex Luthor
- Madison Riley as Tara Van-El
- Antagonists: Lex Luthor, D.I.S.C.O.R.D., Lucy Lane, Lillian Luthor
- Veronica was last seen in Sometimes. This is her first appearance outside of The Originals (tv series).
- This episode is Lex-centric, while the B-plot focuses on Zod, and the protagonists are given the C-plot.
- This is the first episode to focus on an antagonist who is not part of the main cast.
MAIN CHARACTER SCENE COUNT
- Kara- scenes
- Alex- scenes
- Winn- scenes
- Lena- scenes
- Astra- scenes
- Kal- scenes
- Lucy- scenes
- Maggie- scenes
- Karen- scenes
- James- scenes