|Season 5, Episode 3|
|Fear The Fever||Used To|
PART 3 OF 3: DESAAD UPS HIS GAME- When Maggie discovers the corpses of three clergymen in a seemingly small cult ritual, Desaad kidnaps her in exchange for Reign. Kara and Alex go to extremes to keep Desaad from continuing his killing spree while pursuing a third option. Indigo battles Clark while James comforts a despondent Karen. Lena gives Lillian an answer.
- Melissa Benoist as Kara Danvers/Supergirl
- Chyler Leigh as Alex Danvers
- Jeremy Jordan as Winslow Schott
- Katie McGrath as Lena Luthor
- Odette Annable as Reign
- Tyler Hoechlin as Clark Kent/Superman
- Floriana Lima as Maggie Danvers
- with Claire Holt as Karen Starr/Power Girl
- and Mehcad Brooks as James Olsen
- Laura Vandervoort as Indigo
- Yael Groblas as Psi
- Brenda Strong as Lillian Luthor
- DB Woodside as Desaad
- Amy Jackson as Imra Ardeen
- and Dianna Agron as Major Raya Zod-El
- Antagonists: Desaad, Indigo
- This episode is named after the song by Digital Daggers.
- 3rd episode this season to feature all main characters.
- This episode takes place on November 7, 2020.