|Season 6, Episode 1|
|The Last Daughter of Krypton||The Justice League of America (episode)|
EVIL KARA RISES- Team Supergirl discovers that Reign's last act has caused a new problem: the personification of Kara's darkness and negative qualities. Kara Danvers struggles to accept the return of J'onn J'onzz and ruminates over his offer of joining a fledgling team of superheroes.
- Melissa Benoist as Kara Danvers/Supergirl & Dark Kara
- Chyler Leigh as Alex Danvers
- Katie McGrath as Lena Luthor
- Odette Annable as Reign (corpse, dreams)
- Tyler Hoechlin as Clark Kent/Superman
- Olivia Wilde as Susannah Russo
- Jenna Dewan as Lucy Lane
- Minka Kelly as Dawn Granger
- Claire Holt as Karen Starr/Power Girl
- Michael Rosenbaum as LX-52 & President Lex Luthor (Earth-30)
- with Emmy Rossum as Zaora Dru-Zod
- with David Harewood as J'onn J'onzz
Special Guest StarEdit
- Helen Slater as Eliza Danvers
- Antagonist: Dark Kara
- Reign has no dialogue in this episode.
- This episode takes place on January 2, 2021.