|Season 3, Episode 4 (44)|
KAREN COMES TO NATIONAL CITY- When Karen arrives in National City, Kara attempts to get the disoriented and violent Kryptonian under control while introducing her to the many things she loves. Meanwhile, Alura speaks with Lena, Astra helps Alex and J'onn fend off an attack by Cyborg Superman, and Max Lord meets up with Lucy and Lesla.
- Melissa Benoist as Kara Danvers/Supergirl
- Chyler Leigh as Alex Danvers
- Jeremy Jordan as Winn Schott
- Katie McGrath as Lena Luthor
- Laura Benanti as Alura Zor-El & Astra In-Ze
- Zachary Quinto as General Dru-Zod
- Tyler Hoechlin as Cyborg Superman
- Odette Annable as Samantha Arias/Reign
- Jenna Dewan as Lucy Lane
- with Claire Holt as Karen Starr
- and David Harewood as J'onn J'onzz
Special Guest Star
- Peter Facinelli as Max Lord
- Chad Lowe as Thomas Coville
- Harry Lennix as Commander Fer-Gor
- Paige Turco as Lara Lor-Van
- Casper Crump as Vandal Savage
- Lauren German as President Veronica Banks
- Andrea Brooks as Eve Teschmacher
- Emma Tremblay as Ruby Arias
- Tracy Spiridakos as Lesla-Lar
- Briana Venskus as Agent Susan Vasquez
- Robert Gant as Zor-El
- with Emmy Rossum as Zaora Dru-Zod
- and Dianna Agron as Raya Zod-El
- Antagonists: Cyborg Superman, Thomas Coville
- Clark does not appear in this episode.
- Cat was last seen in Lines.
- This episode takes place June 4, 2020.