|Season 6, Episode 8|
|The Sun Also Rises||The Crime Syndicate|
HE'S BACK- Alien bounty hunter Lobo returns to Earth on the hunt for Karen Starr, prompting Alex Danvers to reach out to Slade Wilson (Earth 3) at a costly price. Elsewhere, Clark Kent and Lois Lane celebrate their first wedding anniversary and LX-52 settles into his new role.
- Melissa Benoist as Kara Danvers/Supergirl
- Chyler Leigh as Alex Danvers
- Katie McGrath as Lena Luthor
- Odette Annable as Reign (credit only)
- Tyler Hoechlin as Clark Kent/Superman
- Olivia Wilde as Susannah Russo (credit only)
- Jenna Dewan as Lucy Lane
- Minka Kelly as Dawn Granger
- Claire Holt as Karen Starr/Power Girl
- Michael Rosenbaum as LX-52
- with Emmy Rossum as Zaora Dru-Zod (credit only)
- with Mehcad Brooks as James Olsen/Guardian
- and David Harewood as J'onn J'onzz (credit only)
Special Guest StarsEdit
- Jason Momoa as Lobo
- Max Martini as Slade Wilson (Earth-3)/Deathstroke
- Elizabeth Tulloch as Lois Lane
- Antagonist: Lobo
- Reign, Susannah, Zaora, and J'onn do not appear in this episode.
- This episode is February 4, 2021.